C. diff.

Clostridium Difficile, aka “C. diff.”

C. diff. is a species of Gram-positive bacteria that causes serious diarrhea and other intestinal diseases. C. diff. is the common name for Clostridium difficile, or “C. difficile.” This disease occurs when opposing bacteria in the gut flora are eliminated by antibiotics. When these bacteria are wiped out, it leads to the development of C. diff.


C. diff. is the most severe cause of antibiotic-associated diarrhea and can lead to pseudomebranous colitis. Pseudomebranous colitis is a serious inflammation of the colon. This often results from elimination of the regular gut flora by antibiotics.


C. diff bacteria are naturally found in the gut in a small percentage of the adult population. However, most people accidentally ingest C. diff. spores when they are patients in a hospital, nursing home, or similar facility.  In fact, about 14,000 people die each year in America because of C. diff. contracted in a hospital.


When the normal gut flora in the colon are destroyed, usually as a result of an antibiotic like clindamycin, the gut becomes overrun by C. diff. This overpopulation is dangerous because the bacteria release toxins that cause bloating and diarrhea. These symptoms are also accompanied by abdominal pain. C. diff. infections are the most common cause of pseudomembranous colitis, and in rare cases this can lead to toxic megacolon, which can be life-threatening. Latent symptoms of C. diff. frequently imitate flu-like symptoms and can mimic disease flare in patients with inflammatory bowel disease-associated colitis.


The most common treatment for C. diff. is antibiotics. However, these are a costly and frequently ineffective solution. Fecal Microbiota Transplantation is becoming increasingly accepted as a treatment for C. diff. The current cure rates for this treatment are just under 90%, and RDS infusions is no exception. We have had great success treating C. diff. with FMT.


For more information about FMT as a treatment for  C.. diff. see this article.

Clostridium difficile, C. diff.

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